A meta-analysis of cytokines in Alzheimer's disease

W Swardfager, K Lanctôt, L Rothenburg, A Wong… - Biological …, 2010 - Elsevier
BACKGROUND: Studies suggest that inflammation is involved in the neurodegenerative
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to
quantitatively summarize the clinical cytokine data. METHODS: Original English language
peer-reviewed studies measuring cytokine concentrations in AD and healthy control
subjects were included. Mean (±standard deviation) cytokine concentrations for AD and
control subjects were extracted. RESULTS: Forty studies measuring peripheral blood …